An unusual tandem kinase fusion protein confers leaf rust resistance in wheat
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Tartalom: http://real.mtak.hu/175110/
Archívum: REAL
Gyűjtemény: Status = Published
Type = Article
Subject = S Agriculture / mezőgazdaság: SB Plant culture / növénytermesztés: SB975 Plant protection / növényvédelem
Cím:
An unusual tandem kinase fusion protein confers leaf rust resistance in wheat
Létrehozó:
Wang, Yajun
Abrouk, Michael
Gourdoupis, Spyridon
Koo, Dal-Hoe
Karafiátová, Miroslava
Molnár, István
Holušová, Kateřina
Doležel, Jaroslav
Athiyannan, Naveenkumar
Cavalet-Giorsa, Emile
Jaremko, Łukasz
Poland, Jesse
Krattinger, Simon G.
Kiadó:
Nature Publishing Group
Dátum:
2023
Téma:
SB975 Plant protection / növényvédelem
Tartalmi leírás:
The introgression of chromosome segments from wild relatives is an established strategy to enrich crop germplasm with disease-resistance genes1. Here we use mutagenesis and transcriptome sequencing to clone the leaf rust resistance gene Lr9, which was introduced into bread wheat from the wild grass species Aegilops umbellulata2. We established that Lr9 encodes an unusual tandem kinase fusion protein. Long-read sequencing of a wheat Lr9 introgression line and the putative Ae. umbellulata Lr9 donor enabled us to assemble the ~28.4-Mb Lr9 translocation and to identify the translocation breakpoint. We likewise cloned Lr58, which was reportedly introgressed from Aegilops triuncialis3, but has an identical coding sequence compared to Lr9. Cytogenetic and haplotype analyses corroborate that the two genes originate from the same translocation event. Our work sheds light on the emerging role of kinase fusion proteins in wheat disease resistance, expanding the repertoire of disease-resistance genes for breeding.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Wang, Yajun and Abrouk, Michael and Gourdoupis, Spyridon and Koo, Dal-Hoe and Karafiátová, Miroslava and Molnár, István and Holušová, Kateřina and Doležel, Jaroslav and Athiyannan, Naveenkumar and Cavalet-Giorsa, Emile and Jaremko, Łukasz and Poland, Jesse and Krattinger, Simon G. (2023) An unusual tandem kinase fusion protein confers leaf rust resistance in wheat. NATURE GENETICS, 55. pp. 914-920. ISSN 1061-4036 (print); 1546-1718 (online)
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