| Tartalom: |
http://real.mtak.hu/103473/ |
| Archívum: |
REAL |
| Gyűjtemény: |
Status = Published
Subject = Q Science / természettudomány: QD Chemistry / kémia
Subject = Q Science / természettudomány: QD Chemistry / kémia: QD04 Organic chemistry / szerves kémia
Type = Article
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| Cím: |
1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with
2H‐Azirines: Stereoselective Synthesis of 1,3-
Diazaspiro[bicyclo[3.1.0]hexane]oxindoles
|
| Létrehozó: |
Angyal, Anikó
Demjén, András
Harmat, Veronika
Wölfling, János
Puskás, László G.
Kanizsai, Iván
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| Kiadó: |
American Chemical Society
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| Dátum: |
2019
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| Téma: |
QD Chemistry / kémia
QD04 Organic chemistry / szerves kémia
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| Tartalmi leírás: |
A regio- and diastereoselective 1,3-dipolar cycloaddition of 2H-azirines with azomethine ylides generated in situ from isatins and α-amino acids has been elaborated, affording an unprecedented aziridine-fused spiro[imidazolidine-4,3′-oxindole] framework. This one-pot three-component reaction tolerates a wide range of substrates and enables the construction of highly diverse 1,3-diazaspiro[bicyclo[3.1.0]hexane]oxindoles in isolated yields up to 81% under mild conditions.
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| Nyelv: |
magyar
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| Típus: |
Article
NonPeerReviewed
info:eu-repo/semantics/article
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| Formátum: |
text
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| Azonosító: |
Angyal, Anikó and Demjén, András and Harmat, Veronika and Wölfling, János and Puskás, László G. and Kanizsai, Iván (2019) 1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with 2H‐Azirines: Stereoselective Synthesis of 1,3- Diazaspiro[bicyclo[3.1.0]hexane]oxindoles. JOURNAL OF ORGANIC CHEMISTRY, 84 (7). pp. 4273-4281. ISSN 0022-3263
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| Kapcsolat: |
10.1021/acs.joc.9b00242
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