Alicyclic β- and γ-Amino Acids: Useful Scaffolds for the Stereocontrolled Access to Amino Acid-Based Carbocyclic Nucleoside Analogs
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Tartalom: http://real.mtak.hu/103318/
Archívum: REAL
Gyűjtemény: Status = Published
Subject = Q Science / természettudomány: QD Chemistry / kémia: QD05 Crystallography / kristálytan
Subject = Q Science / természettudomány: QD Chemistry / kémia
Subject = Q Science / természettudomány: QD Chemistry / kémia: QD04 Organic chemistry / szerves kémia
Type = Article
Cím:
Alicyclic β- and γ-Amino Acids: Useful Scaffolds for the Stereocontrolled Access to Amino Acid-Based Carbocyclic Nucleoside Analogs
Létrehozó:
Remete, Attila Márió
Kiss, Loránd
Kiadó:
MDPI
Dátum:
2019
Téma:
QD Chemistry / kémia
QD04 Organic chemistry / szerves kémia
QD05 Crystallography / kristálytan
Tartalmi leírás:
Stereocontrolled synthesis of some amino acid-based carbocyclic nucleoside analogs containing ring C=C bond has been performed on β- and γ-lactam basis. Key steps were N-arylation of readily available β- or γ-lactam-derived amino ester isomers and amino alcohols with 5-amino- 4,6-dichloropyrimidine; ring closure of the formed adduct with HC(OMe)3 and nucleophilic displacement of chlorine with various N-nucleophiles in the resulting 6-chloropurine moiety.
Nyelv:
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Remete, Attila Márió and Kiss, Loránd (2019) Alicyclic β- and γ-Amino Acids: Useful Scaffolds for the Stereocontrolled Access to Amino Acid-Based Carbocyclic Nucleoside Analogs. MOLECULES. ISSN 1420-3049
Kapcsolat:
Létrehozó:
cc_by