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Hplc determination of enantiomeric purity of protected amino acid derivatives used in peptide synthesis |
| Tartalom: | http://publicatio.bibl.u-szeged.hu/31995/ |
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| Archívum: | SZTE Publicatio Repozitórium |
| Gyűjtemény: |
Állapot = Megjelent
Típus = Folyóiratcikk |
| Cím: |
Hplc determination of enantiomeric purity of protected amino acid derivatives used in peptide synthesis
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| Létrehozó: |
Szókán Gyula
Hadfi S
Krizsán Krisztina
Liembeck A
Krecz I
Almás M
Somlai Csaba
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| Dátum: |
1994
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| Téma: |
03.02. Klinikai orvostan
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| Tartalmi leírás: |
An improved RP-HPLC method on ODS-Hypersil column with precolumn derivatization with Marfey's reagent were used to monitor racemization in N-, C- and/or side-chain protected amino acid derivatives by separation of a series of new diastereoisomeric Marfey's compounds. Chromatographic samples were obtained by partial deprotection of different starting materials. In a simple two-step procedure (deprotection and derivatization) the compounds of amino acids formed stable diastereomeric derivatives having facile resolutions.
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| Nyelv: |
angol
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| Típus: |
Folyóiratcikk
PeerReviewed
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| Formátum: |
text
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| Azonosító: |
Szókán Gyula; Hadfi S; Krizsán Krisztina; Liembeck A; Krecz I; Almás M; Somlai Csaba: Hplc determination of enantiomeric purity of protected amino acid derivatives used in peptide synthesis.
JOURNAL OF LIQUID CHROMATOGRAPHY, 17 (13). pp. 2759-2775. ISSN 0148-3919 (1994)
doi:10.1080/10826079408013498
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| Kapcsolat: |
1880327
info:eu-repo/semantics/altIdentifier/doi/10.1080/10826079408013498
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| Létrehozó: |
info:eu-repo/semantics/restrictedAccess
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