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SUMMARY
The authors present the process of bacterial and fungal biofilm formation and
its clinical significance, based on literature data. Biofilms are microorganism
colonies embedded in an extracellular matrix, where microbes differ in physiology
compared to their free-living planktonic counterparts. Biofilms are more
resilient against environmental factors, including antibiotics and antiseptics.
Besides their importance in human medicine they are primarily found in therapy
resistant skin, ear and mammary gland infections in the veterinary field. The
authors present the structural development, and the regulatory mechanisms
of biofilm formation, and in addition, the usage of anti-biofilm agents in the
veterinary medicine.
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