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A módosított, a mátrixhoz kötött és intakt mikotoxinok egységes fogalomrendszere és a mátrixhoz kötött mikotoxinok alternatív meghatározása - Rövid áttekintés
Unitary definition of the modified, matrix-associated and free mycotoxins and alternative determination of the matrix-associated mycotoxins - Mini review
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| Tartalmi leírás: |
SUMMARY
The healthy organism is able to transform a relatively high proportion of mycotoxins.
The original molecular form of some mycotoxins may be altered via the
enzymatic xenobiotic transformation ability of the liver, or even by the intestinal
microbiota, but in some instances as early as the site of production by the
mould or in the host plant they may be transformed, as well. Moreover, divergent
chemical effects may play a role in the modification of the original chemical
form. Along this process, the emerging new molecules can be more toxic and
biologically more active than the parent compound. The hidden (bound) mycotoxin
theory is rather new. For the clarification of the erroneously and unequivocally
used terminology in the year 2014, a new, systematic definition criterion
has been worked out, in which mycotoxins are classified into four hierarchic
levels, based on their formation. This mini review introduces this classification
system with numerous examples and shows alternative method for the preparation
of samples before analysis of matrix associated mycotoxins.
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