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Kapcsolat
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A consistency criterion for EQ-5D-5L bolt-on valuation |
| Tartalom: | https://unipub.lib.uni-corvinus.hu/13426/ |
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| Archívum: | Corvinus Kutatások |
| Gyűjtemény: |
Status = Published
Subject = Social welfare, insurance, health care Type = Article |
| Cím: |
A consistency criterion for EQ-5D-5L bolt-on valuation
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| Létrehozó: |
Jakubczyk, Michał
Rencz, Fanni
Rand, Kim
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| Kiadó: |
Springer
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| Dátum: |
2026
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| Téma: |
Social welfare, insurance, health care
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| Tartalmi leírás: |
Objective
EuroQol is developing the EQ-5D Bolt-on Toolbox, an experimental set of bolt-ons designed to improve the sensitivity of EQ-5D-5L in specific populations. For use in cost-utility analyses, EQ-5D-5L+bolt-on value sets should be consistent with EQ-5D-5L value sets. This study proposes a method to define and maintain such consistency and examines its properties.
Methods
We developed a novel contraction method that defines consistency using the distribution of disutilities in measurement data and estimates a contraction parameter from the conditional distribution of bolt-on levels given the core EQ-5D-5L profile to account for information overlap. The method was tested for nine bolt-ons: breathing, cognition, hearing, self-confidence, skin irritation, sleep, social relationships, tiredness, and vision. We used general-population samples from 14 countries, with 10,395–42,206 observations per bolt-on, and patient samples from six disease areas, with 312–2,486 observations. Core-dimension disutilities were based on the UK EQ-5D-5L value set, and bolt-on disutilities were taken from published studies. Associations of the contraction parameter with bolt-on disutilities and core-dimension correlations were assessed using linear regression.
Results
Achieving consistency required contraction factors ranging from 0.871 for breathing to 0.989 for sleep. Stronger contraction was required for bolt-ons with larger disutilities and for those more strongly correlated with the core dimensions, although only the former association was statistically significant.
Conclusion
The contraction method aligns EQ-5D-5L+bolt-on value sets with EQ-5D-5L value sets, reducing potential double counting while preserving the increased sensitivity provided by bolt-ons.
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| Nyelv: |
angol
angol
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| Típus: |
Article
PeerReviewed
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| Formátum: |
application/pdf
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| Azonosító: |
Jakubczyk, Michał ORCID: https://orcid.org/0000-0002-0006-6769 <https://orcid.org/0000-0002-0006-6769>, Rencz, Fanni ORCID: https://orcid.org/0000-0001-9674-620X <https://orcid.org/0000-0001-9674-620X> and Rand, Kim ORCID: https://orcid.org/0000-0001-7692-4099 <https://orcid.org/0000-0001-7692-4099> (2026) A consistency criterion for EQ-5D-5L bolt-on valuation. European Journal of Health Economics, 2026 . DOI 10.1007/s10198-026-02009-z <https://doi.org/10.1007/s10198-026-02009-z>
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| Kapcsolat: |
10.1007/s10198-026-02009-z
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