Genetic diversity and adaptability of native sheep breeds from different climatic zones
  • Metaadatok
Tartalom: https://unipub.lib.uni-corvinus.hu/13133/
Archívum: Corvinus Kutatások
Gyűjtemény: Status = Published
Subject = Genetics
Type = Article
Cím:
Genetic diversity and adaptability of native sheep breeds from different climatic zones
Létrehozó:
Wanjala, George
Bagi, Zoltán
Gavojdian, Dinu
Badaoui, Bouabid
Astuti, Putri Kusuma
Mizeranschi, Alexandru
Ilisiu, Elena
Ohran, Husein
Juhas, Eva Pasic
Loukovitis, Dimitrios
Kawęcka, Aldona
Šveistienė, Rūta
Becskei, Zsolt
Strausz, Péter
Kichamu, Nelly
Kusza, Szilvia
Kiadó:
Springer Nature
Dátum:
2025
Téma:
Genetics
Tartalmi leírás:
To better understand the genetic architecture and adaptability of native sheep, 22 breeds were genotyped using ovine50K SNP chips. Eleven additional populations from open-source repositories were included. Cross population Extended Haplotype Homozygosity (XP-EHH) and Relative Scaled Haplotype Homozygosity (Rsb) haplotype-based approaches were used to identify genetic variations influencing the adaptation of local sheep breeds to different climatic zones. The results indicate that all breeds exhibited high but declining genetic diversity levels, with a larger proportion of genetic variation explained by development history and refined by geographical origin, as shown by principal component analysis and Neighbor Net graphs. Admixture analysis revealed high admixture levels in European and North African breeds. Using XP-EHH and Rsb methods, 371 genes were putatively under selection, with only nine common among all population pairs, highlighting unique adaptability. Most identified genes, including Interleukin (IL) and cluster differentiation (CD) gene families underlie immune responses, emphasizing their role in resilience to climate change effects. These findings support that indigenous sheep breeds have retained significant genetic diversity, but improper genetic management may threaten it. Additionally, the research emphasizes that indigenous sheep breeds’ unique adaptability to specific climatic zones makes them valuable genetic assets for developing climate-resilient breeds.
Nyelv:
angol
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
application/pdf
Azonosító:
Wanjala, George ORCID: https://orcid.org/0000-0001-7818-2412 <https://orcid.org/0000-0001-7818-2412>, Bagi, Zoltán ORCID: https://orcid.org/0000-0002-3832-3556 <https://orcid.org/0000-0002-3832-3556>, Gavojdian, Dinu, Badaoui, Bouabid, Astuti, Putri Kusuma ORCID: https://orcid.org/0000-0002-2589-5811 <https://orcid.org/0000-0002-2589-5811>, Mizeranschi, Alexandru, Ilisiu, Elena, Ohran, Husein, Juhas, Eva Pasic, Loukovitis, Dimitrios, Kawęcka, Aldona, Šveistienė, Rūta, Becskei, Zsolt, Strausz, Péter ORCID: https://orcid.org/0000-0002-5676-5606 <https://orcid.org/0000-0002-5676-5606>, Kichamu, Nelly and Kusza, Szilvia ORCID: https://orcid.org/0000-0002-5441-5303 <https://orcid.org/0000-0002-5441-5303> (2025) Genetic diversity and adaptability of native sheep breeds from different climatic zones. Scientific Reports, 15 (1). DOI https://doi.org/10.1038/s41598-025-97931-2
Kapcsolat:
info:eu-repo/grantAgreement/EC/H2020/772787
Létrehozó:
cc_by_4
info:eu-repo/semantics/openAccess